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Peptides

Suitable Skin Types

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Normal Skin


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Dry Skin


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Oily & Acne Skin


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Combination Skin


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Sensitive Skin


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Highlights of Peptides

  • Fortify skin barrier
  • Enhance skin elasticity and stimulates collagen production
  • Improves skin texture, smoothness and hydration
  • Antimicrobial – fights off bacteria that causes acne
  • Anti-inflammatory
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What are Peptides?

Peptides are short chains of amino acids (the building blocks of proteins), and are naturally found in our skin. In skincare, these versatile ingredients are often synthesised or derived from natural sources to address a variety of concerns. These concerns can range from signs of ageing and hydration to firmness and texture.

Signal peptides and carrier peptides are two well-known examples. Signal peptides act as messengers, stimulating skin cells to produce collagen or elastin, essential components for a youthful appearance.1 Carrier peptides, on the other hand, function as delivery vehicles, transporting other beneficial ingredients deeper into the skin for enhanced effectiveness.

While identifying peptides on ingredient lists can be challenging, some helpful clues exist. Many peptide names will end with the word “peptide” or begin with “palmitoyl.” However, there are exceptions. Hydrolyzed collagen and glutathione, for instance, are both peptides but don’t follow this naming convention.

What can Peptides do for your skin?

Anti-Ageing: Certain peptides, like palmitoyl pentapeptide-4 (Matrixyl), palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7, stimulate collagen production. This can improve skin firmness and reduce the appearance of fine lines and wrinkles.2

Skin Renewal: Copper peptides (copper tripeptide-1) and palmitoyl hexapeptide-12 can promote skin renewal and regeneration, resulting in a smoother and more radiant complexion.3

Hydration: Peptides like palmitoyl tripeptide-5 and acetyl hexapeptide-37 can attract and retain moisture in the skin, keeping it hydrated.

Soothing Relief: Some peptides, including acetyl tetrapeptide-15 and palmitoyl tripeptide-8, possess anti-inflammatory properties that can help reduce redness and soothe irritation.4

Can you use Peptides when you’re pregnant?

While topical application of peptides is generally considered safe, pregnant and breastfeeding individuals may want to exercise caution before incorporating it into their skincare routine. Peptides are often formulated with other active ingredients such as retinol and salicylic acids which should be avoided during pregnancy. We strongly advise consulting your healthcare provider before introducing products containing peptides into your skincare routine.
A white tube of Naked Chemist Spot Cover concealer with precision applicator for seamless coverage and spot correction.

How do you use Peptides?

Peptides function best when they remain on the skin for a sustained period, allowing for deeper penetration and enhanced absorption. Formulations in serums, moisturisers, toners and leave-on masks deliver the best results. While peptides offer a multitude of benefits, it’s important to note that they aren’t meant to work alone. Combining them with other supportive ingredients like ceramides, hyaluronic acid, retinols and antioxidants creates a more comprehensive skincare regimen. This synergy allows peptides to maximise their effectiveness, leading to a healthier and more radiant complexion.5

Similar to vitamin C, products containing peptides require specific packaging to maintain their effectiveness. Airtight and opaque containers are essential to protect them from light and air exposure, which can degrade their potency. That being said, get ready to be amazed by Mizon’s Collagen 100 ampoule, a firm favourite that gives you visible skin firming results, or achieve smooth and bouncy skin with OOTD’s Peptide Skin Barrier Cream. Let’s not forget the restorative powers of Bonajour’s outstanding new Retichinol Power Concentrate and Retichinol Power Boosting Serum designed to plump and enhance skin elasticity, all without irritation.

Sources

1 Ngoc, Le Thi Nhu, Ju-Young Moon, and Young-Chul Lee. 2023. “Insights into Bioactive Peptides in Cosmetics” Cosmetics 10, no. 4: 111. Link

2 Robinson, L. R., Fitzgerald, N. C., Doughty, D. G., Dawes, N. C., & Berge, C. A. (2005). Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. International Journal of Cosmetic Science. Link

3 Pickart, L. Margolina, A. Int. J. Mol. Sci. 2018. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Link

4 Resende, D. I. S. P., Ferreira, M. S., Sousa-Lobo, J. M., Sousa, E., & Almeida, I. F. (2021). Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel, Switzerland), 14(8), 702. Link

5 Escobar, S., Valois, A., Nielsen, M., Closs, B., & Kerob, D. (2021). Effectiveness of a formulation containing peptides and vitamin C in treating signs of facial ageing: three clinical studies. International journal of cosmetic science, 43(2), 131–135. Link
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